Acne scar study, 2012

Trial centre

Dept. of Dermatology, Peking University First Hospital, Beijing, China.


An exploratory study to assess the efficacy of Bi-Oil in improving the appearance of facial acne scars on Chinese subjects.


Subjects: 44 Chinese subjects with newly formed acne scars on the face (<1 year old). Bi-Oil treatment cell included 32 subjects and the no treatment cell included 12 subjects. Age of participants: 14 to 30.


Randomised, controlled, efficacy grader-blinded. Subjects participated in an initial screening evaluation followed by a 1-week washout period. Product applied twice daily for 10 weeks. Application performed under supervision at regular intervals. Assessments conducted at 0, 4, 8 and 10 weeks included the following: Global scarring score (GSS) assessment by the investigator, measurement of acne scar colour / redness using a chromameter, measurement of sebum levels using a sebumeter, documentation of number of comedones and inflammatory lesions by a dermatologist. Subjects also completed self-assessment questionnaires at each visit.


The best result of the clinical grading was in Bi-Oil’s ability to reduce the erythema or redness of macular (flat) acne scars, with the overall skin becoming brighter. Results of the self-assessment questionnaire showed that more than 84% of subjects experienced an improvement in the overall condition of their acne scars and more than 90% experienced an improvement in scar colour. Acne count and sebum measurement results showed that using Bi-Oil does not cause or aggravate acne or increase sebum secretion.